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[49.714765486623897,0.81859347048300501]
[49.955190578059899,0.81961497804521]
[50.195615669496,0.82114723938851797]
[50.556253306650099,0.82012573182631299]
[50.736572125227099,0.82012573182631299]
[51.067156625951696,0.82097698812815101]
[51.337634853817299,0.81987035493576199]
[51.578059945253301,0.81961497804521]
[51.818485036689403,0.81961497804521]
[52.058910128125497,0.81961497804521]
[52.299335219561499,0.81961497804521]
[52.529742598854398,0.81961497804521]
[52.840291675292697,0.82114723938851797]
[53.050663630299198,0.820250243942104]
[53.331159570308003,0.81961497804521]
[54,0.81961497804521]
[55,0.81961497804521]
[56,0.81961497804521]
[0.82294757665677598,0.98513986013985999]
[7.8180019782393604,0.95716783216783197]

{"sheet":"est_summary","index":1,"n_rows":3,"n_cols":8,"rows_kept":3,"cut":false,"hidden":false,"merged":[]}
["HR for death"]
["HR","HR est","LB","LB est","HB","HB est","p","p est"]
[0.37,0.3765,0.18,0.1855,0.77,0.76400000000000001,4.0000000000000001E-3,6.8199999999999997E-3]

{"sheet":"flex_fit","index":2,"n_rows":263,"n_cols":26,"rows_kept":263,"cut":false,"hidden":false,"merged":[]}
["arm_0  \"sham control\"",null,null,null,null,null,null,null,null,"arm_0  \"sham control\""]
["Распределение","AIC","AIC, №","BIC","BIC, №","Coeff. 1","Coeff. 2","Coeff. 3",null,"week","Weibull","Gompertz","Log-logistic","Lognormal","Generalised Gamma","Exponential","est KM data",null,"week","Weibull","Gompertz","Log-logistic","Lognormal","Generalised Gamma","Exponential","est KM data"]
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["Gompertz",183.43709999999999,{"$f":"_xlfn.RANK.AVG(B4,B$3:B$8,1)","v":3},186.86429999999999,{"$f":"_xlfn.RANK.AVG(D4,D$3:D$8,1)","v":3},-3.0106910000000001E-2,{"$f":"EXP(-3.80363654)","v":2.2289567390613524E-2},null,null,1,{"$f":"Fnc_Survival(K$2,$J4,VLOOKUP(K$2,$A$3:$H$8,6,FALSE),VLOOKUP(K$2,$A$3:$H$8,7,FALSE),VLOOKUP(K$2,$A$3:$H$8,8,FALSE))","v":0.97862282638841125},{"$f":"Fnc_Survival(L$2,$J4,VLOOKUP(L$2,$A$3:$H$8,6,FALSE),VLOOKUP(L$2,$A$3:$H$8,7,FALSE),VLOOKUP(L$2,$A$3:$H$8,8,FALSE))","v":0.9782819339138572},{"$f":"Fnc_Survival(M$2,$J4,VLOOKUP(M$2,$A$3:$H$8,6,FALSE),VLOOKUP(M$2,$A$3:$H$8,7,FALSE),VLOOKUP(M$2,$A$3:$H$8,8,FALSE))","v":0.98352379223845965},{"$f":"Fnc_Survival(N$2,$J4,VLOOKUP(N$2,$A$3:$H$8,6,FALSE),VLOOKUP(N$2,$A$3:$H$8,7,FALSE),VLOOKUP(N$2,$A$3:$H$8,8,FALSE))","v":0.99279754737243076},{"$f":"Fnc_Survival(O$2,$J4,VLOOKUP(O$2,$A$3:$H$8,6,FALSE),VLOOKUP(O$2,$A$3:$H$8,7,FALSE),VLOOKUP(O$2,$A$3:$H$8,8,FALSE))","v":0.99999986199487312},{"$f":"Fnc_Survival(P$2,$J4,VLOOKUP(P$2,$A$3:$H$8,6,FALSE),VLOOKUP(P$2,$A$3:$H$8,7,FALSE),VLOOKUP(P$2,$A$3:$H$8,8,FALSE))","v":0.98737964902083231},1,null,1,{"$f":"Fnc_Survival(T$2,$J4,VLOOKUP(T$2,$A$12:$H$18,6,FALSE),VLOOKUP(T$2,$A$12:$H$18,7,FALSE),VLOOKUP(T$2,$A$12:$H$18,8,FALSE))","v":0.98890904976281913},0.99012606571229833,0.98978345273868995,0.99378661533838997,0.99681525009775207,0.99535084095384763,0.98750000000000004]
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["Lognormal",183.0342,{"$f":"_xlfn.RANK.AVG(B6,B$3:B$8,1)","v":2},186.46129999999999,{"$f":"_xlfn.RANK.AVG(D6,D$3:D$8,1)","v":2},4.0696826000000001,{"$f":"EXP(0.5087004)","v":1.6631283882051626},null,null,3,{"$f":"Fnc_Survival(K$2,$J6,VLOOKUP(K$2,$A$3:$H$8,6,FALSE),VLOOKUP(K$2,$A$3:$H$8,7,FALSE),VLOOKUP(K$2,$A$3:$H$8,8,FALSE))","v":0.94621959080817819},{"$f":"Fnc_Survival(L$2,$J6,VLOOKUP(L$2,$A$3:$H$8,6,FALSE),VLOOKUP(L$2,$A$3:$H$8,7,FALSE),VLOOKUP(L$2,$A$3:$H$8,8,FALSE))","v":0.93806335644065242},{"$f":"Fnc_Survival(M$2,$J6,VLOOKUP(M$2,$A$3:$H$8,6,FALSE),VLOOKUP(M$2,$A$3:$H$8,7,FALSE),VLOOKUP(M$2,$A$3:$H$8,8,FALSE))","v":0.95146984453100336},{"$f":"Fnc_Survival(N$2,$J6,VLOOKUP(N$2,$A$3:$H$8,6,FALSE),VLOOKUP(N$2,$A$3:$H$8,7,FALSE),VLOOKUP(N$2,$A$3:$H$8,8,FALSE))","v":0.96298555164097588},{"$f":"Fnc_Survival(O$2,$J6,VLOOKUP(O$2,$A$3:$H$8,6,FALSE),VLOOKUP(O$2,$A$3:$H$8,7,FALSE),VLOOKUP(O$2,$A$3:$H$8,8,FALSE))","v":0.98326625802747869},{"$f":"Fnc_Survival(P$2,$J6,VLOOKUP(P$2,$A$3:$H$8,6,FALSE),VLOOKUP(P$2,$A$3:$H$8,7,FALSE),VLOOKUP(P$2,$A$3:$H$8,8,FALSE))","v":0.96261475675458086},0.95120000000000005,null,3,0.97445788460855187,0.97185416937760261,0.97524627470392034,0.97900814959721782,0.98040244647390362,0.98611726641096797,0.98750000000000004]
["Generalised Gamma",181.9391,{"$f":"_xlfn.RANK.AVG(B7,B$3:B$8,1)","v":1},187.07980000000001,{"$f":"_xlfn.RANK.AVG(D7,D$3:D$8,1)","v":4},2.3592445999999998,{"$f":"EXP(0.3895037)","v":1.4762479501848447},-2.8359999999999999,null,4,{"$f":"Fnc_Survival(K$2,$J7,VLOOKUP(K$2,$A$3:$H$8,6,FALSE),VLOOKUP(K$2,$A$3:$H$8,7,FALSE),VLOOKUP(K$2,$A$3:$H$8,8,FALSE))","v":0.93174500638340951},{"$f":"Fnc_Survival(L$2,$J7,VLOOKUP(L$2,$A$3:$H$8,6,FALSE),VLOOKUP(L$2,$A$3:$H$8,7,FALSE),VLOOKUP(L$2,$A$3:$H$8,8,FALSE))","v":0.91943228387496534},{"$f":"Fnc_Survival(M$2,$J7,VLOOKUP(M$2,$A$3:$H$8,6,FALSE),VLOOKUP(M$2,$A$3:$H$8,7,FALSE),VLOOKUP(M$2,$A$3:$H$8,8,FALSE))","v":0.93609191402626712},{"$f":"Fnc_Survival(N$2,$J7,VLOOKUP(N$2,$A$3:$H$8,6,FALSE),VLOOKUP(N$2,$A$3:$H$8,7,FALSE),VLOOKUP(N$2,$A$3:$H$8,8,FALSE))","v":0.94667750795694883},{"$f":"Fnc_Survival(O$2,$J7,VLOOKUP(O$2,$A$3:$H$8,6,FALSE),VLOOKUP(O$2,$A$3:$H$8,7,FALSE),VLOOKUP(O$2,$A$3:$H$8,8,FALSE))","v":0.95792406393676077},{"$f":"Fnc_Survival(P$2,$J7,VLOOKUP(P$2,$A$3:$H$8,6,FALSE),VLOOKUP(P$2,$A$3:$H$8,7,FALSE),VLOOKUP(P$2,$A$3:$H$8,8,FALSE))","v":0.95046622066661179},0.95120000000000005,null,4,0.96826185653122254,0.96340002376273515,0.96887434158272978,0.97203799495479359,0.97191533934610796,0.98153265040126647,0.98750000000000004]
["Exponential",184.44739999999999,{"$f":"_xlfn.RANK.AVG(B8,B$3:B$8,1)","v":4},186.161,{"$f":"_xlfn.RANK.AVG(D8,D$3:D$8,1)","v":1},{"$f":"EXP(-4.366101)","v":1.2700664043433193E-2},null,null,null,5,{"$f":"Fnc_Survival(K$2,$J8,VLOOKUP(K$2,$A$3:$H$8,6,FALSE),VLOOKUP(K$2,$A$3:$H$8,7,FALSE),VLOOKUP(K$2,$A$3:$H$8,8,FALSE))","v":0.91800118269119857},{"$f":"Fnc_Survival(L$2,$J8,VLOOKUP(L$2,$A$3:$H$8,6,FALSE),VLOOKUP(L$2,$A$3:$H$8,7,FALSE),VLOOKUP(L$2,$A$3:$H$8,8,FALSE))","v":0.90170758188989275},{"$f":"Fnc_Survival(M$2,$J8,VLOOKUP(M$2,$A$3:$H$8,6,FALSE),VLOOKUP(M$2,$A$3:$H$8,7,FALSE),VLOOKUP(M$2,$A$3:$H$8,8,FALSE))","v":0.92115324577730928},{"$f":"Fnc_Survival(N$2,$J8,VLOOKUP(N$2,$A$3:$H$8,6,FALSE),VLOOKUP(N$2,$A$3:$H$8,7,FALSE),VLOOKUP(N$2,$A$3:$H$8,8,FALSE))","v":0.93046822592585965},{"$f":"Fnc_Survival(O$2,$J8,VLOOKUP(O$2,$A$3:$H$8,6,FALSE),VLOOKUP(O$2,$A$3:$H$8,7,FALSE),VLOOKUP(O$2,$A$3:$H$8,8,FALSE))","v":0.93001743656851887},{"$f":"Fnc_Survival(P$2,$J8,VLOOKUP(P$2,$A$3:$H$8,6,FALSE),VLOOKUP(P$2,$A$3:$H$8,7,FALSE),VLOOKUP(P$2,$A$3:$H$8,8,FALSE))","v":0.93847100336795608},0.878,null,5,0.96245805624107561,0.95536609960721175,0.96286480527390583,0.96538797046638114,0.96383303487817773,0.97696934900055954,0.98750000000000004]
[null,null,null,null,null,null,null,null,null,6,{"$f":"Fnc_Survival(K$2,$J9,VLOOKUP(K$2,$A$3:$H$8,6,FALSE),VLOOKUP(K$2,$A$3:$H$8,7,FALSE),VLOOKUP(K$2,$A$3:$H$8,8,FALSE))","v":0.90484710922584632},{"$f":"Fnc_Survival(L$2,$J9,VLOOKUP(L$2,$A$3:$H$8,6,FALSE),VLOOKUP(L$2,$A$3:$H$8,7,FALSE),VLOOKUP(L$2,$A$3:$H$8,8,FALSE))","v":0.88483526924187816},{"$f":"Fnc_Survival(M$2,$J9,VLOOKUP(M$2,$A$3:$H$8,6,FALSE),VLOOKUP(M$2,$A$3:$H$8,7,FALSE),VLOOKUP(M$2,$A$3:$H$8,8,FALSE))","v":0.90664523280814824},{"$f":"Fnc_Survival(N$2,$J9,VLOOKUP(N$2,$A$3:$H$8,6,FALSE),VLOOKUP(N$2,$A$3:$H$8,7,FALSE),VLOOKUP(N$2,$A$3:$H$8,8,FALSE))","v":0.91460372346862351},{"$f":"Fnc_Survival(O$2,$J9,VLOOKUP(O$2,$A$3:$H$8,6,FALSE),VLOOKUP(O$2,$A$3:$H$8,7,FALSE),VLOOKUP(O$2,$A$3:$H$8,8,FALSE))","v":0.90319209613700813},{"$f":"Fnc_Survival(P$2,$J9,VLOOKUP(P$2,$A$3:$H$8,6,FALSE),VLOOKUP(P$2,$A$3:$H$8,7,FALSE),VLOOKUP(P$2,$A$3:$H$8,8,FALSE))","v":0.92662716992168082},0.878,null,6,0.95695400483194015,0.94772879539907229,0.95714064864159276,0.9590354845242306,0.95620978541519097,0.97242726311383998,0.97499999999999998]
[null,null,null,null,null,null,null,null,null,7,{"$f":"Fnc_Survival(K$2,$J10,VLOOKUP(K$2,$A$3:$H$8,6,FALSE),VLOOKUP(K$2,$A$3:$H$8,7,FALSE),VLOOKUP(K$2,$A$3:$H$8,8,FALSE))","v":0.89219045066724501},{"$f":"Fnc_Survival(L$2,$J10,VLOOKUP(L$2,$A$3:$H$8,6,FALSE),VLOOKUP(L$2,$A$3:$H$8,7,FALSE),VLOOKUP(L$2,$A$3:$H$8,8,FALSE))","v":0.86876521570832499},{"$f":"Fnc_Survival(M$2,$J10,VLOOKUP(M$2,$A$3:$H$8,6,FALSE),VLOOKUP(M$2,$A$3:$H$8,7,FALSE),VLOOKUP(M$2,$A$3:$H$8,8,FALSE))","v":0.89255590033967247},{"$f":"Fnc_Survival(N$2,$J10,VLOOKUP(N$2,$A$3:$H$8,6,FALSE),VLOOKUP(N$2,$A$3:$H$8,7,FALSE),VLOOKUP(N$2,$A$3:$H$8,8,FALSE))","v":0.89919436529369223},{"$f":"Fnc_Survival(O$2,$J10,VLOOKUP(O$2,$A$3:$H$8,6,FALSE),VLOOKUP(O$2,$A$3:$H$8,7,FALSE),VLOOKUP(O$2,$A$3:$H$8,8,FALSE))","v":0.87856786693485955},{"$f":"Fnc_Survival(P$2,$J10,VLOOKUP(P$2,$A$3:$H$8,6,FALSE),VLOOKUP(P$2,$A$3:$H$8,7,FALSE),VLOOKUP(P$2,$A$3:$H$8,8,FALSE))","v":0.91493280981043623},0.878,null,7,{"$f":"Fnc_Survival(T$2,$J10,VLOOKUP(T$2,$A$12:$H$18,6,FALSE),VLOOKUP(T$2,$A$12:$H$18,7,FALSE),VLOOKUP(T$2,$A$12:$H$18,8,FALSE))","v":0.95169124664562454},0.94046605705291442,0.95165211596633681,0.95295436904107089,0.94903481495564779,0.96790629410680917,0.96250000000000002]
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[]
["Overall survival"]
["arm, model / week",0,13,26,39,52,56,{"$f":"2*52","v":104},{"$f":"3*52","v":156},{"$f":"4*52","v":208},{"$f":"5*52","v":260}]
["placebo, est KM data",{"$f":"VLOOKUP(B$3,flex_fit!$J$2:$Q$263,8,FALSE)","v":1},{"$f":"VLOOKUP(C$3,flex_fit!$J$2:$Q$263,8,FALSE)","v":0.78049999999999997},{"$f":"VLOOKUP(D$3,flex_fit!$J$2:$Q$263,8,FALSE)","v":0.65310000000000001},{"$f":"VLOOKUP(E$3,flex_fit!$J$2:$Q$263,8,FALSE)","v":0.55649999999999999},{"$f":"VLOOKUP(F$3,flex_fit!$J$2:$Q$263,8,FALSE)","v":0.55649999999999999},{"$f":"VLOOKUP(G$3,flex_fit!$J$2:$Q$263,8,FALSE)","v":0.55649999999999999}]
["placebo, gengamma (AIC best)",{"$f":"VLOOKUP(B$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":1},{"$f":"VLOOKUP(C$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.77284297821462555},{"$f":"VLOOKUP(D$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.65930147498083358},{"$f":"VLOOKUP(E$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.59923139893150124},{"$f":"VLOOKUP(F$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.55970417342321888},{"$f":"VLOOKUP(G$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.5499309959522809},{"$f":"VLOOKUP(H$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.47452824763900153},{"$f":"VLOOKUP(I$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.4307664092954866},{"$f":"VLOOKUP(J$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.40217401230205607},{"$f":"VLOOKUP(K$3,flex_fit!$J$2:$Q$263,6,FALSE)","v":0.38130576532097471}]
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["nusinersen, est KM data",{"$f":"VLOOKUP(B$3,flex_fit!$S$2:$Z$263,8,FALSE)","v":1},{"$f":"VLOOKUP(C$3,flex_fit!$S$2:$Z$263,8,FALSE)","v":0.8992},{"$f":"VLOOKUP(D$3,flex_fit!$S$2:$Z$263,8,FALSE)","v":0.85909999999999997},{"$f":"VLOOKUP(E$3,flex_fit!$S$2:$Z$263,8,FALSE)","v":0.81240000000000001},{"$f":"VLOOKUP(F$3,flex_fit!$S$2:$Z$263,8,FALSE)","v":0.81240000000000001},{"$f":"VLOOKUP(G$3,flex_fit!$S$2:$Z$263,8,FALSE)","v":0.81240000000000001}]
["nusinersen, Gompertz (AIC and BIC best)",{"$f":"VLOOKUP(B$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":1},{"$f":"VLOOKUP(C$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.90368754967662313},{"$f":"VLOOKUP(D$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.85247709859944498},{"$f":"VLOOKUP(E$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.82430551846780786},{"$f":"VLOOKUP(F$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.80850193686536898},{"$f":"VLOOKUP(G$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.80518927322869505},{"$f":"VLOOKUP(H$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.78979727202130445},{"$f":"VLOOKUP(I$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.78776429278119731},{"$f":"VLOOKUP(J$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.78754075716822458},{"$f":"VLOOKUP(K$3,flex_fit!$S$2:$Z$263,3,FALSE)","v":0.78751614706114592}]